Thriyv: Aftercare Information Sheet – Polynucleotides
Purpose
This guide provides information on what to expect following your polynucleotide treatment and how to care for your skin to promote effective healing and optimal results.
Immediately After Treatment
You may experience mild redness, swelling, or small bumps at the injection sites. These are normal and typically resolve within 24–48 hours. Bruising and tenderness may occur, especially in delicate areas such as under the eyes, but these effects are temporary.
Aftercare Advice
- Avoid touching, rubbing, or applying pressure to the treated area for at least 24 hours.
- Do not apply makeup for 24 hours following treatment.
- Avoid alcohol, caffeine, and strenuous exercise for 24 hours, as these can increase swelling or bruising.
- Refrain from saunas, steam rooms, sunbeds, and hot baths for 48 hours.
- Avoid facials, massages, or skin treatments for at least 7 days.
- Use a gentle cleanser and avoid active skincare (retinol, acids, exfoliants) for 24 hours.
- Keep the treated area clean and hydrated.
Skin Care and Hydration
Polynucleotides work by stimulating collagen and elastin production and improving hydration. To support this process:
Drink plenty of water for at least 48 hours after treatment.
Apply a gentle, non-perfumed moisturiser.
Always use SPF 30 or higher to protect the skin from UV exposure.
Healing and Results
Some mild swelling or bruising may be visible for a few days. Results develop gradually as the skin regenerates, with visible improvement typically after 2–3 weeks. The full benefit is seen after completing your treatment course. Skin will appear more hydrated, smoother, and firmer over time.
Possible Side Effects
Most side effects are mild and temporary. These can include redness, swelling, bruising, or tenderness. Rarely, infection or small nodules can develop at injection sites. If any unusual symptoms occur, contact the clinic immediately.
When to Contact the Clinic
- Please contact Thriyv straight away if you experience:
- Increasing redness, swelling, or pain at the injection sites.
- Persistent lumps or warmth that may indicate infection.
- Fever or general unwellness after treatment.
- Any concerns that seem unusual or severe.
Maintenance and Ongoing Care
To maintain the benefits of polynucleotide treatment, complete the full course recommended by your clinician and consider maintenance sessions every 6–9 months. Combining treatment with a consistent skincare routine and sun protection will further support results.
Contact Information
Telephone: 0161 566 5099
Email: info@thriyv.co.uk
Website: www.thriyv.co.uk
Clinic Address
Thriyv
14–16 Whitworth Street
Manchester
M1 3BS
Thank you for choosing Thriyv for your polynucleotide treatment. We look forward to supporting you throughout your skin rejuvenation journey.

