Walk into any high street health shop and you’ll find shelves heaving with supplements. Most are underdosed. Many use inferior ingredient forms chosen for cost, not bioavailability. A worrying number make claims that wouldn’t survive clinical review.
At Thriyv, we took a different approach. Every product in our doctor-formulated supplements range was developed by Dr Callum Shields MBChB, our Medical Director, with one filter applied to every decision: would I prescribe this to a patient in my clinic?
That single question removed shortcuts. It meant clinical doses, evidence-backed ingredient forms, without comprimise. The result is a five-product range built for adults who take their health seriously — each supplement targeting a specific physiological system, designed to stack into a coherent protocol for longevity, recovery, and daily resilience.
In this post we introduce Thriyv’s supplement range and who they are most suited to.
The Foundation is the cornerstone of the Thriyv range — a comprehensive marine-sourced multi-nutrient designed to fill the gaps a modern diet routinely leaves behind.
Most multivitamins use the cheapest possible nutrient forms: magnesium oxide, cyanocobalamin, dl-alpha tocopherol. These are technically the nutrient on the label, but they’re poorly absorbed and, in some cases, biologically inactive until your body converts them. Dr Shields rejected this approach during formulation.
The Foundation uses methylated B vitamins (methylfolate and methylcobalamin) for people whose genetics make standard B12 and folate harder to use, PureSea® organic marine multi-mineral complex as the base mineral source, vitamin D3 with K2 (MK-7) rather than D3 alone, and chelated forms of zinc and magnesium for genuine absorption.
Anyone over 30 who wants a clinical-grade daily multi-nutrient without the guesswork. It’s the supplement Dr Shields takes himself. Contains fish-derived ingredients. Not suitable for those with seafood allergies.
Your liver processes everything — alcohol, medications, environmental toxins, the by-products of your own metabolism. The Cleanser was formulated to support the body’s natural detoxification pathways, particularly Phase II liver conjugation, where most over-the-counter “detox” products fall short.
The marketing of detox supplements is, frankly, a problem in this industry. Dr Shields built this product to do something specific and measurable: support glutathione production, optimise milk thistle delivery, and provide the cofactors your liver actually needs to function under modern load.
Key ingredients include Silybin Phytosome® for vastly superior milk thistle absorption, N-acetyl cysteine (NAC) at a clinically relevant 600mg dose as the precursor to glutathione, alpha-lipoic acid for antioxidant recycling, and a full B-complex to support methylation — the engine of Phase II detoxification.
Patients dealing with high alcohol intake, regular medication use, environmental exposure, or anyone wanting to support liver function as part of a longevity stack. Not a “cleanse” — a daily liver-support supplement designed for sustained use.
Sleep is when your body does its repair work. Yet sleep supplements on the market are dominated by single-ingredient melatonin pills or proprietary blends that hide doses. The Restoration is neither.
Dr Shields formulated this product around a simple clinical observation: most patients reporting poor recovery weren’t deficient in any one thing — they were under-supplied across the whole calming-and-restoring pathway. Magnesium for muscle relaxation, glycine for core body temperature drop, L-theanine for parasympathetic activation, apigenin for deep sleep architecture.
The formulation delivers magnesium glycinate at 300mg elemental magnesium (the form that crosses the blood-brain barrier without causing gut upset), glycine at 3g (the dose shown in sleep studies to improve subjective sleep quality), L-theanine at 200mg for evening calm without sedation, and apigenin at 50mg derived from chamomile.
Anyone whose recovery isn’t keeping pace with their training, work demands, or life stress. Particularly useful for clinic patients combining red light therapy or cryotherapy with structured recovery protocols.
NMN (nicotinamide mononucleotide) is the most-studied longevity molecule of the last decade. It’s the direct precursor to NAD+, the coenzyme your cells use to produce energy and repair DNA — and the molecule your body produces less of every year after 30.
The Renewal is Thriyv’s flagship longevity supplement: 500mg of pharmaceutical-grade NMN per serving, formulated to align with the dosing used in human longevity research. Below 250mg shows limited NAD+ elevation in blood plasma. Above 1g shows diminishing returns at significantly increased cost. 500mg sits in the clinically meaningful sweet spot used in trials at Harvard and Keio University.
Dr Shields chose Uthever®-grade NMN — third-party tested for 99%+ purity, with full certificates of analysis available on request. Regulatory note: NMN status in the UK is currently being assessed by the MHRA under novel food regulations. Thriyv supplies The Renewal in compliance with current UK guidance.
Adults over 35 building a longevity protocol. Stacks particularly well with The Foundation (cofactors for NAD+ pathways) and The Restoration (sleep is when most cellular repair occurs).
The final supplement in the range is The Shield — a comprehensive immune and antioxidant formula built around the principle that immunity isn’t a single switch you flip when you feel a cold coming on. It’s a system that needs daily inputs to function.
The product mainstream brands won’t make is exactly the product Dr Shields wanted to create here: clinical doses of well-researched immune nutrients, with no proprietary blends and no inflated claims.
The formulation provides vitamin C at 1000mg in a buffered gentler-on-the-gut form, zinc picolinate at 15mg (the most bioavailable zinc form), vitamin D3 at 4000 IU for those not getting adequate sun exposure, quercetin at 500mg for respiratory support and zinc ionophore activity, selenium as selenomethionine for thyroid and immune cofactor support, and standardised elderberry extract.
Year-round daily support for adults wanting evidence-based immune protection. Particularly useful during autumn and winter, for frequent travellers, and for patients with high training loads where immune dips are common.
Thriyv Wellness & Aesthetics is located in the heart of Manchester City Centre, right between Manchester Piccadilly Train Station and Kampus.
We’re just a few moments walk from major rail, tram and bus hubs, with a multi-story carpark next door. This means its never been easier to start your journey at Thriyv, whether you’re based in Manchester City Centre or travelling from further afield.
Our full address is Thriyv, 14-16 Whitworth Street, Manchester, M1 3BS. See you soon!
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