IV drip therapy and 10-minute intramuscular injections at our Whitworth Street clinic in Manchester. Every treatment is doctor-led and given by our clinical team, and your first visit starts with a clinical consultation. Most drips take about an hour. Prices from £40.
If you want numbers before an infusion plan, start with blood testing Manchester at the same Whitworth Street clinic.
CQC registered for diagnostic and screening procedures
Dr Callum Shields, MBChB, LLM, MPhil, MRCS (ENT), Medical Director, GMC 7668672
Every IV vitamin therapy protocol at Thriyv is medically supervised by Dr Callum Shields (MBChB, LLM, MPhil, MRCS (ENT)) and tailored to your health profile after a clinical consultation. Explore our doctor-led IV drip menu and vitamin injections in Manchester city centre.
Our Most Intensive IV Protocol
For a longevity-focused wellness routine. NAD+ is a coenzyme involved in cellular energy metabolism, offered following clinical assessment with our team.
Book NAD ReplenishAntioxidant IV Drip
For a skincare and wellbeing routine. Glutathione is an antioxidant made naturally by the body.
Book Glutathione — Detox & GlowVitamin & Mineral Blend
For travel, training or a general wellbeing routine. An all-round drip combining magnesium, calcium, B vitamins and vitamin C.
Book Myers’ — Total HydrationHigh-Dose Vitamin C — Skin & Immunity
For antioxidant support, with the dose chosen with you at consultation. High-dose vitamin C by IV may support the body’s normal antioxidant defences.
Book Vitamin C — Skin & ImmunityB-Complex Vitamin Infusion
For a skin, energy and healthy-ageing routine. B vitamins help reduce tiredness and fatigue, support the normal function of the nervous system and contribute to the maintenance of normal skin, with biotin supporting normal hair too.
Each 50mL drip contains nicotinamide 40mg, dexpanthenol 6mg, thiamine hydrochloride 10mg, pyridoxine hydrochloride 4mg, riboflavin sodium phosphate 5.5mg, methylcobalamin 1mg, biotin 0.2mg and folic acid 0.2mg.
Book Anti-Ageing DripAn IM injection is a single injection into a muscle, given by our clinical team. Each appointment takes 10 minutes, and your suitability is checked at consultation. Course prices are listed on each card.
Vitamin B12 · Intramuscular
Vitamin B12 given as a single injection into the muscle.
Book B12 injectionNAD+ 50mg · Intramuscular
Our lower NAD+ dose, given as a single injection into the muscle.
Book NAD+ 50mg injectionNAD+ 100mg · Intramuscular
Our higher NAD+ dose, given as a single injection into the muscle.
Book NAD+ 100mg injectionChoose based on what you want to get out of your treatment — your practitioner will confirm the right protocol for you at consultation.
This is a general guide, not medical advice — your suitability for any IV treatment is confirmed by our clinical team following a consultation.
Thriyv is located in the heart of Manchester City Centre, and every visit begins with a proper clinical consultation rather than a walk-in drip. Before your first IV vitamin therapy session, a member of our clinical team will review your medical history to confirm the treatment is suitable for you, and talk you through how the drip works, including anything you need to know.
Finally, you’ll read and sign your treatment consent form, confirming you’re happy to proceed.
At Thriyv, IV vitamin therapy is run as a clinical service. Every infusion protocol is reviewed and overseen by our Medical Director, Dr Callum Shields (MBChB, LLM, MPhil, MRCS (ENT)), and every client completes a clinical consultation before their first drip.
We use pharmaceutical-grade ingredients, prepared and given by our clinical team in a clean, private treatment room on Whitworth Street. Thriyv is CQC registered for diagnostic and screening procedures.
Most people can head straight back into your day in Manchester city centre after IV vitamin therapy at Thriyv. Most sessions take between 30 and 60 minutes, and our clinical team will explain what to expect afterwards as part of your aftercare.
If you have any questions once you’ve left the clinic, our team is on hand to help. Aftercare advice and an individual treatment plan are part of every visit.
Just finished your IV therapy treatment session and looking for new ways to level up your wellness game? Or are you building towards an aesthetic goal and wondering how you can take your skin to the next level?
Thriyv offers a suite of wellness, aesthetics and skincare services meaning you can continue your journey with us and feel rejuvenated both inside and out!
Intravenous (IV) vitamin therapy delivers vitamins, minerals and other nutrients directly into your bloodstream through a drip, so they bypass the digestive system. At our clinic on Whitworth Street, each infusion protocol is medically supervised and chosen with you after a clinical consultation. Some people use IV therapy as part of a wider wellbeing routine.
At Thriyv, patient safety and clinical governance come first. Every IV protocol, from NAD Replenish to our Anti-Ageing Drip, is overseen by our Medical Director, Dr Callum Shields (MBChB, LLM, MPhil, MRCS (ENT)). Treatments are prepared to medical-grade standards and given in a clean, clinical treatment room by our trained clinical team.
Yes. To ensure your safety and to customise your treatment, every client at our Manchester city centre clinic undergoes a mandatory clinical consultation before their first infusion. During this assessment, we review your medical history, discuss your wellness goals, and identify any specific nutrient deficiencies. Under the clinical guidance of Dr Callum Shields, we then formulate a personalised infusion programme tailored precisely to your physiological needs.
A typical IV therapy session at Thriyv takes between 45 and 60 minutes. During this time, you can relax in our modern, welcoming clinic environment on Whitworth Street. For our intramuscular (IM) injections, such as Vitamin B12, the appointment takes 10 minutes. Most people have no downtime after either treatment and can return to your day in Manchester straight after their session.
During your initial consultation, our clinical team will talk through your lifestyle, goals and medical history before recommending a protocol. For clients interested in cellular energy and longevity-focused wellness, we may discuss our NAD Replenish infusion. For those who train regularly or want a general wellbeing option, some people choose the Myers’ — Total Hydration or Glutathione — Detox & Glow.
Side effects from IV vitamin therapy are usually mild. Some clients notice a cool feeling in the arm during the infusion, or slight bruising at the entry site, which usually settles quickly. Your clinician will talk you through the possible risks at your consultation. Every protocol is overseen by Dr Callum Shields (MBChB, LLM, MPhil, MRCS (ENT)), and our team follows strict clinical procedures for preparation and administration.
Pricing varies by treatment, and our current prices are shown above. The NAD Replenish drip is £275 for 250mg or £425 for 500mg, IM NAD+ injections start from £50, and our Anti-Ageing Drip is £225. Our clinical team will discuss exact pricing and suitability with you before you book.
Some people should avoid or delay IV therapy, including pregnant women and those with certain heart, kidney or blood pressure conditions. This is exactly why every client at Thriyv completes a clinical consultation and medical history review before treatment, so any contraindications are identified in advance.
NAD (nicotinamide adenine dinucleotide) is a coenzyme found in every cell in the body, involved in cellular energy metabolism. It’s a popular choice for clients interested in longevity-focused wellness routines, and is offered at our Manchester clinic as part of our doctor-led IV drip menu.
This depends on the drip, your individual health and your goals. For IV therapy Manchester and IV drips Manchester clients, we’ll discuss a sensible frequency during consultation rather than a one-size-fits-all schedule.
They work differently rather than one simply being “better”. Oral supplements are absorbed through the digestive system, while IV therapy delivers nutrients directly into the bloodstream. Which approach is appropriate for you depends on your individual circumstances, which we’ll discuss at your consultation.
Some clients choose our B12 injection or Myers’ — Total Hydration drip as part of their routine for everyday tiredness. Persistent or ongoing fatigue should always be discussed with your GP first, as it can have a number of underlying causes.
Some athletes and gym-goers in Manchester choose a Glutathione — Detox & Glow or Myers’ — Total Hydration IV drip as part of a wider routine alongside rest, nutrition and hydration.
All IV vitamin therapy protocols at Thriyv are overseen by our Medical Director, Dr Callum Shields (MBChB, LLM, MPhil, MRCS (ENT)), and treatments are given by trained clinical staff.
Thriyv is CQC registered for diagnostic and screening procedures. Our clinic is at 14-16 Whitworth Street, Manchester, M1 3BS.
Thriyv Wellness & Aesthetics is located in the heart of Manchester City Centre, right between Manchester Piccadilly Train Station and Kampus.
We’re just a few moments’ walk from major rail, tram and bus hubs, with on-site parking at the Piccadilly Q-Park directly above the clinic. This means it’s never been easier to start your journey at Thriyv, whether you’re based in Manchester City Centre or travelling from further afield.
Our full address is Thriyv, 14-16 Whitworth Street, Manchester, M1 3BS. See you soon!
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Medically reviewed by Dr Callum Shields, Medical Director · Last reviewed 6 October 2026
